{"id":3125,"date":"2022-09-22T13:30:56","date_gmt":"2022-09-22T13:30:56","guid":{"rendered":"https:\/\/www.screenpharma.it\/sedazepam-food-supplement\/"},"modified":"2023-07-05T07:55:25","modified_gmt":"2023-07-05T07:55:25","slug":"sedazepam-food-supplement","status":"publish","type":"post","link":"https:\/\/www.screenpharma.it\/en\/sedazepam-food-supplement\/","title":{"rendered":"Sedazepam Food Supplement"},"content":{"rendered":"

<\/div>insomnia is a growing and important health problem, <\/strong>If it persisted, it could have a negative impact on people’s well-being. Today we have a wide range of techniques for measuring and analyzing sleep quality and quantity. The purpose of this work is to demonstrate the impact of nutrition in sleep disorders. Methods: literature review selecting the most relevant articles related to nutrition and its impact on sleep. Findings: there is a direct correlation between certain foods or supplements and sleep quality and quantity. In addition, there are some nutritional pointers that can help prevent or solve some sleep disorders. The relationship of tryptophan and melatonin with the induction and maintenance of sleep is clear, but vitamins, minerals, macronutrients, and certain dietary habits may also be affected. Conclusions: nutrition can have a relevant effect in the prevention and resolution of sleep disorders. THE ROLE OF MELATONIN<\/strong> In mammals, a central circadian clock, located in the suprachiasmatic nuclei (SCN) of the hypothalamus, tunes innate circadian physiological rhythms to the 24-hour environmental light-dark cycle to invigorate and optimize internal temporal order. Melatonin production activated by SCN and inhibited by light transmits the message of darkness to the clock and induces the physiological functions of the night state, e.g., sleep\/wake blood pressure and metabolism. Clinically significant effects of melatonin treatment have been demonstrated in placebo-controlled studies in humans, particularly in disorders associated with reduced or misaligned melatonin rhythms, e.g., circadian rhythm-related sleep disturbances, jet lag and shift work, insomnia in children with neurodevelopmental disorders , poor (nonrestorative) sleep quality, nighttime blood pressure without drops (nocturnal hypertension), and Alzheimer’s disease (AD). As a result of the newly discovered relationship between the circadian clock, sleep, and neurodegeneration, new perspectives emerge for the use of melatonin for early intervention, and to promote healthy physical and mental aging, which are of paramount importance in view of the emerging link to the etiology of Alzheimer’s disease. FORMULATIVE RATIONALE SEDAZEPAM<\/strong> aims as its first “therapeutic” outcome to achieve those results that, as we saw in the previous section, are achievable with the use of melatonin. We are going to associate the following functional assets with it: GRIFFONIA SIMPLICIFOLIA<\/strong> This botanical sepecies is recognized by all the world’s pharmacopoeias for its proven “therapeutic” properties. The seeds of griffonia,in fact, contain 5-hydroxy-tryptophan (5-HTP), a precursor of serotonin, the “feel-good hormone,” which in our bodies is involved in various physiological functions, including the regulation of mood, sleep and appetite. Serotonin is a neurotransmitter synthesized by our body from tryptophan, an amino acid defined as “essential” because the human body is unable to produce it, and for this reason it can only be taken in through food. 5-HTP is an intermediate step in this synthesis, so by taking Griffonia, it is possible to naturally increase serotonin levels in the body. Griffonia is used today with good results as a natural antidepressant for the treatment of mild to moderate depression; in states of anxiety; in seasonal depression and in insomnia, as it raises serotonin levels and regularizes the sleep-wake cycle .(circadian rhythm)<\/p>\n

BIBLIOGRAPHY<\/strong><\/p>\n

Nutrition impact on insomnia treatment]<\/strong><\/p>\n

[Article in Spanish]<\/p>\n

Ovidio Hernando-Requejo<\/a> <\/sup>
\n 1<\/a>
\n<\/sup>, Virgilio Hernando-Requejo<\/a> <\/sup>
\n 2<\/a>
\n<\/sup>, Ana Mar\u00eda Requejo Marcos<\/a> <\/sup>
\n 3<\/a>
\n<\/sup><\/p>\n